The Expedition 52 crew embarked on tasks Wednesday to further NASA’s eventual journey to Mars and aid researchers in understanding how to stimulate cancer-fighting drugs to target cancer cells—and cancer cells alone—in the human body.
The astronauts lent their opinions to a food questionnaire designed to explore if the current food available in the spaceflight food system would be acceptable for even longer-duration missions, like a Martian sojourn. Their input will help develop strategies to improve futuristic food systems in support of crew health and performance.
Of even greater magnitude to Earthlings approximately 240 miles below the orbiting laboratory is the work being performed with the Efficacy and Metabolism of Azonafide Antibody-Drug Conjugates in Microgravity (ADCs in Microgravity) investigation. The crew retrieved a BioCell Habitat, inoculation kits and ADC samples from a Minus Eighty Degree Celsius Laboratory Freezer for ISS (MELFI), set up hardware inside the Microgravity Science Glovebox (MSG) and inoculated the Multiwall BioCells using syringes. Later, the astronauts will repeat these steps with a second BioCell Habitat, which begins an 11-day experiment stretch. In the zero-g environment of space, cancer cells grow in spheroid structures that closely resemble how they form in the human body. This study may speed up the development of targeted therapies for cancer patients, increasing the effectiveness of chemotherapy treatment and while reducing unwanted side effects.
Expedition 52 is taking out the trash midday tomorrow when Russia’s Progress 66 (66P) uncrewed cargo craft departs the International Space Station for a fiery disposal over the Pacific Ocean. The 66P is loaded with garbage and obsolete gear and will undock from the Pirs docking compartment Thursday at 1:46 p.m. EDT. The Russian resupply ship will orbit Earth for a few more hours before reentering Earth’s atmosphere harmlessly over the Pacific. NASA TV will not be covering the undocking activities.
Aboard the International Space Station, Expedition 52 astronauts furthered investigative data for NASA’s Human Research Program, collecting in-flight data and blood and urine samples over the weekend.
Today, the crew will take additional samples for the Biochem Profile, Repository and Cardio Ox investigations. An ultrasound was also used for the Cardio Ox study, which seeks to determine whether biological markers of oxidative and inflammatory stress are elevated during and after spaceflight, and whether this could result in an increased, long-term risk of the hardening of the arteries for space-faring explorers.
Also on tap is the Mag 3D cell culturing experiment. The crew will fixate the BioCells and insert them into the Minus Eighty Degree Celsius Laboratory Freezer for ISS (MELFI). The orbiting laboratory provides a way to manipulate and culture cells in 2D and 3D in space and on the ground, which can help isolate the effects of gravity in experiments and enable biological research previously deemed unfeasible in space.
The next crew to lift off to the International Space Station has arrived at its launch site at the Baikonur Cosmodrome in Kazakhstan. The experienced space travelers from Roscosmos, NASA and ESA (European Space Agency) are due to blast off inside the Soyuz MS-05 spacecraft July 28 for a six-hour ride to the space station’s Rassvet module. Cosmonaut Sergey Ryazanskiy, with astronauts Randy Bresnik and Paolo Nespoli, are scheduled to live and work in space until mid-December.
A pair of astronauts explored new space exercise techniques today to stay healthy and fit on long duration missions. The crew also observed protein crystals and high temperatures to understand microgravity’s effects on humans and physical processes.
Expedition 52 Flight Engineer Jack Fischer strapped himself in to the space station’s exercise bike this morning with assistance from veteran astronaut Peggy Whitson. The work out study is researching the effectiveness of high intensity, low volume exercise to minimize loss of muscle, bone, and cardiovascular function in space.
Whitson, who has been living in space since November 2016, then moved on and set up gear for the Two Phase Flow experiment. That study is observing how heat transfers from liquids in microgravity to help improve the design of thermal management systems in future space platforms.
Fischer later checked out protein crystals through a microscope for an experiment researching radiation damage, bone loss and muscle atrophy caused by living in space. At the end of the day, he swapped out samples that were heated up inside the Electrostatic Levitation Furnace. The furnace is a facility that allows safe observations and measurements of materials exposed to extremely high temperatures.
The orbiting Expedition 52 trio continued exploring magnetized cell structures today and worked on advanced repair tasks. Also, a new crew is in Moscow getting ready for its launch in less than three weeks.
Astronaut Peggy Whitson was back at work Tuesday running the Mag 3D cell culturing experiment all day. She peered at magnetic three-dimensional cell cultures through a microscope, specifically looking at the borders of the biocell structures. The biocells were then stowed in a science freezer before being injected with magnetic 3D culture media. Mag 3D observations may improve cell and tissue culture capabilities and research on orbit.
Though the space station is an orbiting laboratory, it is also a home that needs regular maintenance. Flight Engineer Jack Fischer put on his repairman’s hat today replacing a failed water separator inside the Tranquility module. The water separator is part of the Common Cabin Air Assembly that controls the station’s temperature and humidity.
Three upcoming station crew members are spending their final week in Moscow before heading to the launch site in Kazakhstan on Sunday. The experienced space trio will launch to space aboard the Soyuz MS-05 spacecraft July 28 from the Baikonur Cosmodrome. Expedition 52-53 crew members Randy Bresnik, Paolo Nespoli and Sergey Ryazanskiy will live aboard the station for 4-1/2 months.
The three Expedition 52 crew members practiced evacuating the International Space Station today in the unlikely event of an emergency. The trio also set up an advanced life science study and continued the upkeep of the orbital complex.
Commander Fyodor Yurchikhin joined Flight Engineers Peggy Whitson and Jack Fischer for an emergency evacuation drill Monday morning. The crew practiced quickly donning safety gear and entering the Soyuz MS-04 spacecraft before simulating an emergency undocking and descent to Earth.
Afterward, Whitson spent the rest of the day exploring magnetic cell cultures and bio-printing for the Mag 3D experiment. The new research which just started in April is exploring how magnetic tools may enhance cell and tissue culture capabilities on orbit.
Fischer pressurized the Japanese Kibo lab’s airlock and checked for leaks ahead of an external experiment set to begin next week. Fischer later worked on light plumbing duties and checked on the condition of a science freezer.
Back on Earth, another three Expedition 52 crew members are getting ready for their July 28 launch to the space station. The experienced space trio of Randy Bresnik, Paolo Nespoli and Sergey Ryazanskiy, visited Red Square in Moscow for traditional ceremonies on Monday. They will head to the Baikonur Cosmodrome in Kazakhstan July 16 for final pre-launch training.