ISS Daily Summary Report – 10/09/2020


Onco-Selectors: The crew used the LSG to perform the Onco-Selectors hardware setup, prepare the treatment mixtures, and inject treatments into 12-Well Bio-Cells (S/N 1-5).  12-Well Bio Cell S/N 6 will not be processed and will be placed in cold stowage for return. Leveraging Microgravity to Screen Onco-selective Messenger RNAs for Cancer Immunotherapy (Onco-Selectors) tests a biologic drug based on messenger RNA (mRNA) for treatment of leukemia. This mRNA-based drug is capable of differentiating cancer cells from healthy ones (onco-selective) and is designed to kill cancer cells (oncolytic). Recent studies show that microgravity alters cells by modifying the expression of certain proteins involved in mRNA translation, making it a unique platform for testing mRNAs to identify those that are onco-selective for clinical development.


Systems Operations Data File (SODF) Update: Today, the crew performed an update to the Emergency Response book to incorporate changes to the emergency response procedures. The updates to the procedure account for the upcoming dual Soyuz configuration following 63S arrival.

Completed Task List Activities:

  • Transfer 62S USOS prepack (ongoing)
  • Transfer Cygnus Cargo Operations (ongoing)

Today’s Ground Activities:
All activities are complete unless otherwise noted.

  • Vacuum System (VS) PGT Pressure Bias Update
  • US/RS Audio Configuration for MRM Ops
  • Monthly PCS Reboots and File Downlinks
  • S-Band Index Change
  • Passive Thermal Control System (PTCS) PMA3 Heater Reset
  • Caution and Warning Software State Change (Enable FGB Smoke Warning/SD Failure Caution)

Look Ahead Plan

Saturday, 10/11 (GMT 284)

  • Onco Selectors GLO Reagent (NASA)
  • LSG WV Stow & Restraint Fold (NASA)


  • No Systems Activities

Sunday, 10/12 (GMT 285)

  • Myotones Review (ESA) 


  • Crew Off Duty

Monday, 10/13 (GMT 286)

  • Myotones Ops (ESA)
  • Actiwatch Plus Setup & Swap (NASA)
  • Bacterial Genome Fitness GAP Termination (NASA)


  • KENTAVR Fit Check

Today’s Planned Activities:
All activities are complete unless otherwise noted.

  • KORREKTSIYA. Accelerometry
  • KORREKTSIYA. Log Entry of Liquids and Food (Medicine) Intake
  • Onco-Selectors MELFI Sample Retrieve
  • Countermeasures System (CMS) Advanced Resistive Exercise Device (ARED) Cylinder Flywheel Evacuation
  • ABOUT GAGARIN FROM SPACE. HAM radio pass with Vladivostok
  • ТБУ (Universal Bioengineering Thermostat). Checking ТБУ-В No.07 thermostat temperature and unobstructed area near ТБУ-В inlet/outlet vents
  • ISS crew and ГОГУ (RSA Flight Control Management Team) weekly conference
  • ISS Crew departure preparation
  • [СТТС] Comm Configuration for MRM1
  • SEPARATION. Water distillation from urine in urine water regeneration system [СРВ-У-РС]
  • Onco-Selectors BioCell Transfection
  • MATRYOSHKA-R. Pre-pack BUBBLE-Dosimeter memory card for return to the ground
  • Astrobee Off
  • Airlock Stowage Clear
  • BIODEGRADATSIYA. Sample collection from structure surfaces and photography
  • IDENTIFIKATSIYA. Copy ИМУ-Ц micro-accelerometer data to laptop
  • Hardware prepack for return and disposal on Soyuz 745
  • Health Maintenance System (HMS) ISS Food Intake Tracker (ISS FIT)
  • Systems Operations Data File (SODF) Update