ISS Daily Summary Report – 10/12/2020


Onco-Selectors: Over the weekend the crew completed sample processing operations to prep the 12 well BioCells inside the Life Science Glovebox and inject the Glo Reagent into each of the samples. Leveraging Microgravity to Screen Onco-selective Messenger RNAs for Cancer Immunotherapy (Onco-Selectors) tests a biologic drug based on messenger RNA (mRNA) for treatment of leukemia. This mRNA-based drug is capable of differentiating cancer cells from healthy ones (onco-selective) and is designed to kill cancer cells (oncolytic). Recent studies show that microgravity alters cells by modifying the expression of certain proteins involved in mRNA translation, making it a unique platform for testing mRNAs to identify those that are onco-selective for clinical development.

Myotones (Muscle Tone in Space): The crew completed a Myotones session including blood collection and processing, and used the Myotones scanner to take readings on specific body muscle targets. Myotones investigation observes the biochemical properties of muscles during long-term exposure to the spaceflight environment. Results from this investigation are expected to provide insight into principles of human resting muscle tone, which could lead to the development of new strategies for alternative treatments for rehabilitation both on Earth and for future space missions.

Rhodium Space Rhizosphere: The crew removed the ten sample chambers from the POLAR facilities and placed them in a temporary stowage location within a mesh bag. Soil Health in Space: Determination of Gravitational Effects on Soil Stability for Controlled Environment Agriculture (Rhodium Space Rhizosphere) examines the effects of spaceflight on the soil aggregates formed by fungi and bacteria. Recent studies have shown a connection between biological activity, aggregation formation, and the overall capacity of soils to sustainably produce nutritious food crops. A better understanding of fungal and bacterial structures and functions in soil could improve food production on Earth and in space.

Bacterial Genome Fitness: The crew removed the two Group Activation Packs (GAP) from incubation and terminated the samples and placed the samples into Cold Stowage. Scientists know what happens to plants and animals in microgravity, but understand very little about how bacteria are affected. Most previous research used ground-based techniques to simulate microgravity and looked at only one or two specific bacterial processes. Whole Genome Fitness of Bacteria Under Microgravity (Bacterial Genome Fitness) grows multiple types of bacteria in space and comprehensively examines what processes are important to their growth.


63S Launch and Dock Preparations: Preparations continue for 63S launch and dock planned for this Wednesday, October 14.

Completed Task List Activities:

  • 62S pre-pack [Active]
  • Cygnus cargo ops [Active]

Today’s Ground Activities:
All activities are complete unless otherwise noted.

  • S-Band string 1 configured to hot backup
  • Enable S-Band FDIR Express

Look Ahead Plan

Tuesday, 10/13 (GMT 287)

  • Russian Experiment Sample MELFI insert (ESA)


  • EMU cooling loop scrub
  • Prep for 63S arrival 

Wednesday, 10/14 (GMT 288)

  • FSL-SMD remove and MultiScale Boiling insert (ESA)
  • AWP Watch Don (NASA)
  • ISS HAM Pass (NASA)


  • 63S dock
  • ISS Safety Briefing

Thursday, 10/15 (GMT 289)

  • Handhold Experiment Platform Adapter on MPEP install (NASA)
  • STaARS-12 Kit-ambient stow, Exp Containers into facility (NASA)
  • Rhodium Space Rhizosphere Chamber photo (NASA)
  • Rhodium Space Rhizosphere Chamber to POLAR (NASA)


  • MPEP installation
  • Handhold Exp Platform Adapter install on MPEP

Today’s Planned Activities:
All activities are complete unless otherwise noted.

  • R PAO event report preparation
  • Spotlight Battery and Bulb Remove and Replace
  • Myotones Kit Gathering
  • Myotones Blood Draw and Centrifugation
  • Insertion of Russian experiments blood samples into MELFI
  • Myotones Blood Tube Centrifugation
  • Myotones Centrifuge Spin Conclude
  • Myotones Sample MELFI Insertion
  • Myotones Blood Collection Conclude And Stow
  • Echo Unit Setup for Myotones experiment
  • Actiwatch Plus HRF Rack 2 Setup
  • TBU. Check temperature
  • Myotones Device Setup with EPM Laptop
  • Сomm. check from Baikonur (S/G1)
  • Myotones Measurements
  • СТТС configuration for MRM1
  • Myotones Ultrasound scan using Echo Unit
  • СТТС reconfiguration in MRM1
  • Bacterial Genome Fitness GAP Termination
  • Bacterial Genome Fitness MELFI Sample Insertion
  • Photo T/V (P/TV) Advanced Resistive Exercise Device (ARED) Exercise Video Setup
  • Photo/TV Camcorder Setup Verification
  • Myotones Device Data Transfer
  • Myotones Device Charging using Multi-Port USB Charger
  • Actiwatch Plus HRF Rack 2 Swap
  • ColKA M-03 Bag relocation
  • Rhodium Inflight Biomanufacturing Polar Sample Removal
  • Quick-disconnect screw clamps (БЗВ)tightening in MRM1-FGB
  • Rhodium Inflight Biomanufacturing Science Chamber Ambient Stow
  • Actiwatch Plus HRF Rack 2 Stow
  • Filling ЕДВ (KOВ) for Elektron
  • Replacement БФ СО of Gas analyzer CO ГЛ2106
  • Photo/TV Camcorder Setup Verification
  • ISS Crew departure preparation
  • Echo Unit Stowage
  • Myotones Device Stowage after charging
  • CCE Preparation
  • Crew Choice Event Set Up
  • Crew Choice Event