ISS Daily Summary Report – 11/21/2023


Atmospheric Waves Experiment (AWE): The recently installed external AWE experiment has been activated, but the team is currently working through some data issues at its EXPRESS Logistics Carrier (ELC1) location. From its external space station perch, AWE will focus on colorful bands of light in Earth’s atmosphere, called airglow, to determine what combination of forces drive space weather in the upper atmosphere. Researchers once thought that only the Sun’s constant outflow of ultraviolet light and particles, the solar wind, could affect the region. However, recently they have learned that solar variability is not enough to drive the changes observed, and Earth’s weather also must be having an effect. To help unravel that connection, AWE will investigate how waves in the lower atmosphere, caused by variations in the densities of different packets of air, impact the upper atmosphere. 

Cerebral Aging: The crew performed sampling and media exchanges on the appropriate BioCells. Cell culture media contains nutrients and a pH buffer to sustain cells, and needs to be exchanged periodically as the nutrients are used up and waste products accumulate. The Impact of Spaceflight on Human Brain Ageing Using Cerebral Organoids (Cerebral Ageing) investigation studies the effect of spaceflight and the durability in space of cerebral organoids.  Cerebral organoids are 3D human-derived structures that closely resemble a developing human brain at the molecular and cellular level. Also included for analysis in this investigation are markers of cell stress, metabolism, and ageing in healthy control samples, and cerebral organoids with mutations that lead to accelerated ageing. With this investigation, the research team seeks to establish and validate a pipeline that can be used for experiments with human cells in future long-duration spaceflight.

Complement of Integrated Protocols for Human Exploration Research on Varying Mission Durations (CIPHER): A cognition test was performed, and samples were collected in support of the CIPHER suite of investigations. CIPHER aims to improve our understanding of physiological and psychological changes in humans on missions that range from weeks to one year in duration. Conducting the same research over missions of different durations allows scientists to extrapolate to multi-year missions, such as a three-year round-trip to Mars. These data could provide deeper knowledge about changes that may occur on such missions and support development of countermeasures to promote astronaut health and well-being.

Circadian Light: A Circadian Light end-of-day assessment was performed. The Circadian Light investigation tests a new lighting system, to help astronauts maintain an acceptable circadian rhythm. This can help enhance cognitive performance during a long-duration mission and help combat monotony through automated, varied, and gradually changing lighting sequences and settings.

Sleep in Orbit: The crew participated in two overnight recording sessions for the Sleep in Orbit experiment. The Long-term Sleep Monitoring Before, During and After Extended Spaceflight (Sleep in Orbit) investigation studies the physiological differences between sleep on Earth and in space using ear- Electroencephalography (EEG) based sleep monitoring.

Virtual Reality (VR) Mental Care: The crew reviewed the VR Mental Care Big Picture Words, donned the hardware, and performed an experiment session. The VR Mental Care investigation demonstrates the application of VR for mental relaxation, using 360° high quality (HQ) VR video and sound scenarios delivered via a VR headset. The overall aim is to use VR technology to provide a positive impact on the general mental health of astronauts during a space mission. Investigation activities consist of in-flight testing sessions comprised of VR video viewing and questionnaires (via the ESA EveryWear app).


SpaceX-29 Urine Tank Capacity Test Troubleshooting and Water Fill: Today, the crew completed troubleshooting for the Urine Tank Capacity Test and started water fill activities. Additional activities are expected over the next few days to complete all test objectives.

Health Maintenance System (HMS) On-Orbit Hearing Assessment (OOHA) with KUDUwave Software Setup and Test: The crew performed a hearing test using an OOHA Headset and KUDUwave software. The assessment measures hearing function while crewmembers are exposed to noise and microgravity during long-duration spaceflight.

HMS Tonometry Test Operations: Today, the crew performed Tonometry tests to check their intraocular pressure. Exposure to the microgravity environment results in an initial increase to intraocular pressure which returns to normal over time. The cause and long term effects of this are still unknown making it a high priority study in preparation for long duration space mission to the Moon, and later Mars.

Russian EDV Inspection: Today, the crew performed a visual inspection of a Russian EDV to determine if its contents can be processed through the Urine Processing Assembly (UPA). Imagery of the Russian EDV was downlinked for ground teams to analyze.

Completed Task List Activities:

  • None

Today’s Ground Activities:
All activities are complete unless otherwise noted.

  • JEM Airlock (JEMAL) Payload Operations
  • JEM Remote Manipulator System (JEMRMS) External Facility (JEF) Payload Operations
  • Mobile Transporter (MT) Translation from WS 7 to WS 6

Look Ahead Plan

Wednesday, November 22 (GMT 326)

  • AC2 Touch
  • Cardiobreath
  • Circadian Light
  • JAXA Media Take 4
  • RR-20
  • Sleep in Orbit
  • Space Age
  • STEMonstration
  • VR Mental Care


  • Axiom Smartphone Test
  • WHC Pretreat Tank R&R
  • SpX-29 Urine Tank DTO Tear Down
  • Atmosphere Control and Supply (ACS) Oxygen Manual Valve Open
  • Extravehicular Activity (EVA) Portable Breathing Apparatus (PBA) Relocate
  • Sample Reclamation Operations

Thursday, November 23 (GMT 327)

  • Crew Off Day

Friday, November 24 (GMT 328)

  • AC2 Touch
  • Bacterial Adhesion and Corrosion
  • BFF Facility Clean
  • Cerebral Ageing
  • Cosmic Multishield
  • Immunity Assay
  • Nanoracks MFA (Module-83, -103 remove)
  • SCEM valve Operations
  • VR Mental Care


  • Environmental Health System (EHS) Total Organic Carbon Analyzer (TOCA) Water Recovery System (WRS) Sample Analysis
  • SpX-29 Dragon Cargo Operations
  • Regenerative Environmental Control and Life Support System (ECLSS) Recycle Tank (RT) Drain
  • HMS Spaceflight Cognitive Assessment Tool for Windows (WinSCAT) Test
  • Station Support Computer SSC 9 and 12 Swap

Today’s Planned Activities:
All activities are complete unless otherwise noted.

  • CIPHER Sample Collection Operations
  • Sample Reclamation Operations
  • CIPHER Minus Eighty Degree Laboratory Freezer for ISS (MELFI) Sample Retrieval and Insertion Operations
  • CIPHER HRF Centrifuge Frozen Sample Collection Operations
  • Cerebral Ageing MELFI Sample Retrieve B
  • In-Flight Maintenance (IFM) Life Support Rack (LSR) Ground Strap Inspection
  • Relocation of Adlink Mini PC
  • LSR LAN2 cable reconnection to 20-Port Network Switch Port 11
  • CIPHER Cognition Testing
  • LSG Primary Crew Restraint Unfold
  • 64GB USB Flashdrive Connection
  • Cerebral Ageing Sample Media BXY
  • RR Habitat Restock
  • Cerebral Ageing MELFI Insertion for Fixed Sample BX and Fixed Sample BY
  • Cerebral Ageing Sample Media BXY
  • VR Mental Care session execution
  • OPTIMIS Tablet v1.0.1 Questionnaire
  • LSG Primary Crew Restraint Fold
  • Dragon Cargo Transfer
  • Troubleshooting for SpaceX-29 Urine Tank Assembly
  • SpaceX-29 Urine Tank Capacity Test
  • Russian EDV Inspection
  • OPTIMIS Tablet v1.3.10 Performance Questionnaire
  • SpX-29 Crew Supply Cargo Imagery
  • HMS OOHA with KUDUwave Software Setup and Test
  • Choctaw Heirloom Seeds Imagery and Photo Capture
  • Swap Nikolai iPad with floater iPad [deferred]
  • LSG Work Volume Stow
  • SSC 26 Cable Stowage
  • Deconfigure the drag through used in SpX-29 Dragon and reconfigure the N2 Camera.
  • HMS Tonometry Test Operations
  • WRS CWC-I Degas [deferred]
  • HMS Tonometry MELFI Retrieval and Stow
  • Circadian Light Evening Data Collection
  • Sleep in Orbit pre- and post-measurement activity