This fourth cargo mission by SpaceX will carry the first living creatures: a cadre of mice that will be used in microgravity research on bone density. The mice, part of a collaborative experiment including NASA and the Center for the Advancement of Science in Space (CASIS), will fly to space in their own habitat that will be transferred to the inside of the space station. A company called TechShot developed a Bone Densitometer that will be used to X-ray the mice. The official name of the payload is Rodent Research-1 and you can read more about it here.