Space Innovation and Mobile Healthcare

In today’s A Lab Aloft, our guest blogger is the Director of NASA’s Human Health and Performance Center, Dr. Jeffrey Davis. This center fosters a collaboration between space and Earth research and technologies. Dr. Davis shares with readers the potential behind cooperative efforts during the development stages of projects.

Mobile healthcare is the focus for the upcoming NASA Human Health and Performance Center, or NHHPC, Workshop, scheduled for June 7 in Washington, D.C., as part of D.C. Health Data and Innovation Week. This is our third workshop, and topics of interest include not only terrestrial global health issues, but also technologies for smartphone applications to collect data, to inform patients, to connect patients with their providers, etc.


A collaborative moment from the NASA Human Health and Performance Center Workshop, Jan. 19, 2011. (NASA Image)

For everything developed through the NHHPC, we would like to see an Earth and space application, as well as a transfer of knowledge in both directions. NASA technology could be adapted to terrestrial health issues, via spinoffs and other applications, but we hope to pull in ideas that exist in the public domain for the mutual benefit of everyone. That is the concept behind the center, to connect people and employ that bridge in both directions to benefit spaceflight and life on Earth.

While there are a number of projects ongoing between members, for this blog I am focusing on the Colorimetric Solid Phase Extraction, or CSPE, technology. This is a great example, because it’s different from flying a commercial off-the-shelf device on the International Space Station. It has the potential for development in more than one application.

The CSPE is a paint chip identification device originally designed to match paint colors. The technology was adapted, however, to measure silver and iodine in water and it is now flying on the space station for this purpose. Called the Colorimetric Water Quality Monitoring Kit, this tool enables the measurement of biocides found in water on orbit to allow for safe drinking water for the crew.


NASA astronaut Nicole Stott, Expedition 21 flight engineer, conducts a water quality analysis using the Colorimetric Water Quality Monitoring Kit, or CWQMK, in the Destiny laboratory of the International Space Station. (NASA Image)

There are additional Earth benefits that could derive from the CSPE. It has the potential to be modified to measure arsenic and lead in water, which are global public health concerns. This other capability is not yet developed, but it is a great example of how an innovative design from a non-biomedical piece of equipment can have mutual space and Earth applications.

Through the NHHPC, we hope to find technology applications for space flight or that can use the space station as a testbed for evaluation in later flights. When we are able to fly technologies early in their development on station, we have the benefit of visualizing how the orbiting lab works as a platform for planning purposes.

The inverse of this is that as we continue to learn more about human adaptation to long duration space flight, we can expand that knowledge base through our member organizations and derive how existing NASA technologies or future technologies might adapt for Earth benefits. What we have found is that by approaching problem solving early enough with the NHHPC members, we can preemptively address issues or requirement questions. Creating a device that is low weight, low power and robust parallels many healthcare concerns, especially for remotely located populations.

We find that by asking the right questions, we can connect people in the early phases of technology planning and development. Technology sharing can always occur, but the goal is to identify common issues for use as collaboration platforms that can eventually turn into projects.


The NASA Human Health and Performance Center logo, showing the core goals of collaboration, innovation, and education in global human health and performance efforts in spaceflight between NASA and member institutions. (NASA Image)

The NHHPC is a global, collaborative virtual center designed to convene government, industry, academic, and non-profit organizations that support the advancement of human health and performance innovations for space flight, commercial aviation, and challenging environments on Earth. Our member organizations participate in face-to-face workshops, webcasts, and virtual working groups to address issues, share best practices, and formulate collaborative projects in various areas, including innovation, education, human health and technology development. You can read more about the NHHPC events and developments on our website and follow us on Twitter via @NASAHumanHealth.


Jeffrey R. Davis, MD, MS
NHHPC Director

Johnson Space Center

Jeffrey R. Davis, MD, MS, currently serves as Director, Space Life Sciences, and as the Chief Medical Officer for the NASA’s Johnson Space Center. Dr. Davis’ past positions include Professor, Preventive Medicine and Community Health at the University of Texas Medical Branch; Corporate Medical Director, American Airlines; and Chief, Medical Operations NASA Johnson Space Center.



Remembering Janice Voss

The International Space Station Program Science Office would like to dedicate this entry of A Lab Aloft to the life and work of astronaut Janice Voss, who passed away February 7, 2012. Her support NASA’s vision for science on orbit was a remarkable contribution to our research mission.

Janice Voss, Ph.D., was an astronaut and mission specialist for five space shuttle missions, logging over 49 days in space. These were physical science flights, including STS-83 and STS-94, which were historic re-flights to achieve a singular microgravity research mission. Voss also flew the first “commercial” Spacehab and the radar mapping mission.


June 27, 1993 — Inside the SPACEHAB module, onboard the space shuttle Endeavour, astronaut Janice Voss, STS-57 mission specialist, works with biomaterials products. (Credit: NASA Image STS05739001)

With a real love for physical sciences, Voss used her dedication to research to determine her next role as NASA transitioned from the shuttle era to the station era. Voss was the only crew member ever selected to serve as a Lead Increment Scientist to represent the research community during experiment operations. She worked in this role during Expeditions 8 and 9.  

“Her boundless enthusiasm for getting as much research done was contagious, especially welcome in the challenging time after Columbia,” remembers John Uri, her manager in the ISS Payloads Office at the time. “Her experiences from flying science missions as an astronaut were invaluable in optimizing the onboard research.”


April 4-8, 1997 — Astronaut Janice Voss, payload commander, pictured here following a successful test at the Combustion Module-1. The test was designed to study the Structures of Flame Balls at Low Lewis, or SOFBALL, numbers.
(Credit: NASA Image STS083305017)

The timing of her tenure, which followed the Columbia tragedy, led to one of the more interesting things that happened while Voss was Lead Increment Scientist. While the shuttle was grounded, researchers proposed experiments that could be done with existing materials on orbit.

The International Space Soldering Investigation, or ISSI, was one of these studies performed in microgravity. The crew used the soldering materials they had on orbit to make coupons and melt them, which led to an amazing result! The rosin that was in the solder boiled out to the outside of the coupons, orbiting around them.


In July 2004 astronaut Mike Fincke melts solder onboard the International Space Station. See the full length movies: Windows media format (2 MB), Real video (2 MB), mpeg format (15 MB). (Credit: NASA)

I remember how excited Janice was about this new finding. She worked with scientists to evaluate what caused the orbital effect, with the final determination pointing to Marangoni convection. Voss presented the results in a press briefing, including the incredible video of the experiment.

Later on, as Voss was assigned to different things in the Astronaut Office, she became the ongoing research representative for a number of years. There she represented the crew office, but always with the perspective she carried with her from her time as a Lead Increment Scientist, which made her viewpoint unique.

Voss had a natural scientific curiosity that prompted her to always try different things. She never accepted at face value how things worked, and would try alternatives to investigate further. This questioning nature was an exceptional attribute and helped to make her a success in her many roles with NASA.


Julie A. Robinson, Ph.D.
International Space Station Program Scientist


Part of the Mission, Part of the Science

In today’s A Lab Aloft entry, guest blogger and European Space Agency astronaut Christer Fuglesang talks about his role as a test subject while living aboard the International Space Station.

You may not know it, but being an astronaut also means being a guinea pig. A lot of the research done in space is about humans, in particular how our bodies are affected by the weightlessness. This is important to know in order to prepare ourselves for future human exploration, like when we will travel to Mars. But this research also gives us many new insights in how our bodily systems work. This knowledge can help scientists and doctors to improve medical treatments here on Earth. They can even find new and better ways to prevent illnesses based on microgravity studies.


European Space Agency astronauts Frank De Winne and Christer Fuglesang photographed during the installation of the new Minus Eighty Degree Laboratory Freezer for ISS, or MELFI, in the Destiny laboratory of the International Space Station. (NASA Image)

Virtually every astronaut that has ever gone into space has participated in medical experiments as a test subject – or as I like to call it, a guinea pig. The inhabitants of the International Space Station almost daily have some activity related to human research. During a workout, for instance, we take measurements like blood pressure, heart rate, or body temperature to provide valuable research data.

Some studies, like the Neuroendocrine and Immune Responses in Humans During and After Long Term Stay at ISS, or Immuno, require taking a saliva sample to check the immune system. Then there’s the Nutrition Status Assessment, or Nutrition, which requires blood and urine samples that store in the Minus Eighty Degree Laboratory Freezer for ISS, or MELFI, aboard the station. They later return to the ground for analysis. Another investigation that comes to mind is Bodies In the Space Environment: Relative Contributions of Internal and External Cues to Self – Orientation, During and After Zero Gravity Exposure, or BISE, which measures brainwaves while the astronaut performing some visual tasks to investigate how microgravity affects the neurological system.


European Space Agency astronaut Christer Fuglesang trains for the Otolith Assessment During Postflight Re-adaptation, or Otolith, investigation prior to his departure to the International Space Station. (Credit: Christer Fuglesang)

It seems that almost every system in our bodies gets more or less affected by weightlessness: from muscles and bones to cells in the immune system, from the heart and lungs to eyes and the balance organs in the ears. Humans are designed to live in a 1-g environment, making their long-term exposure to microgravity a fascinating and biologically altering study of the entire body.

In my case, I have specifically participated in several experiments related to the balance system, or vestibular system, such as the Otolith Assessment During Postflight Re-adaptation, or Otolith, and the Ambiguous Tilt and Translation Motion Cues After Space Flight, or Zag. Before and after my flights, I stood on wobbling plates and sat in spinning and sliding chairs, trying to keep my balance or perform some set of actions.

Meanwhile, scientists observed me and compared my responses from before flight with how I performed right after about two weeks in weightlessness. They also looked into how my balance regained normality during the week after returning to Earth. This helped them to understand new things about how humans keep our balance. This  knowledge may eventually help doctors to better diagnose people who have medical disorders like disorientation and nausea.


Canadian astronaut Robert B. Thirsk wears sensors and hardware in preparation for the Canal and Otolith Interaction Study, or COIS, another vestibular system investigation. (NASA Image)

In almost all science, doing an experiment one time is not enough. This is particularly true in human research, since each test subject is somewhat different. Therefore, some 10 other astronauts also performed the above-mentioned experiment. As one can understand, with only so many crew members on orbit at a given time, it takes awhile to get enough guinea pigs to complete a round of human research in space.

These studies are well worth it, however, as is the discomfort of sitting in a chair that spins with 400 rotations per minute while sliding sideways. The research is important and yields unique results for the benefits of humans, both in space and on Earth.


Christer Fuglesang
(NASA)

Christer Fuglesang is an astronaut with the European Space Agency, or ESA. He flew as a Mission Specialist with STS-116 and STS-128 to the International Space Station where he participated in multiple extravehicular activities, or EVAs. He is the first Swedish astronaut to fly in space.

Texas Talks Space

In today’s A Lab Aloft, Jessica Nimon, research communications managing editor for NASA’s International Space Station Program Science Office, talks about the impact of interacting with the public during Space Week 2013 in Austin, Texas.

Texas hosts Space Day at the Capitol in Austin every other year as part of Space Week. This year’s theme was “Human Exploration: the Journey Continues.” This was my second time representing the International Space Station Program Science Office to the students, members of the public and legislative staff who attended. I enjoy participating in such events because not only I can share the latest space station research and technology news, but it also gives me a chance to gauge perceptions from the audience I communicate with in my role as a writer and editor at NASA.

Keeping the exploration theme in mind, NASA’s International Space Station Program research and technology display shared a space with the agency’s Commercial Crew Program and Orion vehicle displays. Joining these exhibits in the lower level of the Capitol building’s rotunda were representatives from various commercial space companies, including SpaceX and Blue Origin. The in-the-round exhibit placement seemed symbolic of the partnerships taking place with NASA to continue and expand human space exploration.


Chelsey Bussey, International Space Station Program Science Office research scientist, answers a student’s questions during Space Day at the Capitol 2013 in Austin, Texas. (NASA/James Blair)

My colleagues, Scientific Communications Analyst Amelia Rai and Research Scientist Chelsey Bussey, helped tell the story of the amazing research, technology and educational opportunities and developments from our orbiting laboratory. We shared how the space station is a resource that goes beyond space exploration goals, reaching out to cross boundaries in areas of healthcare, pharmaceutical advancements and industry spinoffs. Some of my personal favorites to highlight include NeuroArm, a lifesaving robotic instrument for brain surgery developed using technology from the space station’s Canadarm, and advances made in vaccine development.

The inspiration shared at such events has the potential to touch not only the 3rd to 8th grade students targeted by Space Day, but also to inspire the imagination of new users with research goals for microgravity research. While speaking with the people visiting our exhibit, at least one scientist expressed interest in how he could use the space station as a platform for his research.


Amelia Rai, NASA scientific communications analyst, shares International Space Station research and technology facts with a visitor to Space Day at the Capitol 2013 in Austin, Texas. (NASA/Jessica Nimon)

One of the more frequent questions we received during the event had to do with NASA’s collaborative efforts with private businesses. Having our industry partners right next to us in the rotunda provided a great opportunity to share the way NASA does business. Visitors were surprised and excited to hear that NASA is working together with private companies to provide avenues for future exploration, as well as resupply and experiment sample return from the International Space Station.

Space Day followed on the heels of South by Southwest (SXSW), a multiday conference and festival highlighting music, film and technology, which also had a space-themed focus this year. Excitement for exploration was still abuzz all over Austin. Although we didn’t attend SXSW, Amelia, Chelsey and I did have our own follow-up activity by attending an Amateur Radio on the International Space Station (ARISS) event on March 20 at the Ann Richards School for Young Women Leaders in Austin. These students, who were not able to visit the Capitol for Space Day, were excited to have a more up close, personal connection with the space station.


Canadian Space Agency astronaut Chris Hadfield conducts an Amateur Radio on the International Space Station session in the Zvezda Service Module. (NASA)

Using a ham radio contact, which lasts for about 10 minutes, the 540 middle and high school girls were able to listen as their peers asked space-related questions directly to space station Commander Chris Hadfield, who answered from aboard the orbiting laboratory. The audience was so attentive you could hear a pin drop while Hadfield spoke!


Ana H. from the Ann Richards School for Young Women Leaders in Austin, Texas, asks a question for Commander Chris Hadfield to answer during an Amateur Radio on the International Space Station connection.(Catherine Serra-Fuentes)

Project Specialist Monica Martinez organized the ARISS event for the school and commented on the impact such an opportunity has on these young women. “The ARISS contact was an experience that truly wowed our entire student body, faculty and administrative team. The girls thought it was one of the best events of this entire school year and loved talking to Commander Hadfield. They were also so ecstatic to see that he had tweeted about our school right after the contact. Our students were inspired by his words and the overall experience.”


Students at the Ann Richards School for Young Women Leaders in Austin, Texas, pose with NASA International Space Station Program Science Office representatives Jessica Nimon (fourth from left, back row), Chelsey Bussey (fifth from left, back row) and Amelia Rai (sixth from left, back row). (Catherine Serra-Fuentes)

The event was followed by a short space station presentation by Amelia, who shared space station facts and talked about some of the benefits for humanity that have already derived from related research and technology. Amelia’s talk was followed by a short question and answer session where the students’ interest in space-related topics and careers was evident, showing a bright future for human endeavors with space research and exploration.


Jessica Nimon, International Space Station Program Science Office research communications managing editor. (NASA)

Jessica Nimon has a background in the aerospace industry as a technical writer and now works with the International Space Station Program Science Office as the Research Communications Managing Editor. Jessica coordinates and composes Web features, blog entries and manages the @ISS_Research Twitter feed to share space station research and technology news with the public. She has a master’s degree in English from the University of Dallas.

 

The International Space Station: Scientific Melting Pot

In today’s A Lab Aloft entry, guest blogger Assistant International Space Station Program Scientist Kirt Costello shares how the various science disciplines studied aboard the International Space Station can work in concert to enhance research goals.

By now, if you are a follower of this blog or just a follower of the International Space Station, you are familiar with the tremendous international effort it took to assemble this laboratory in orbit and bring its facilities up to their full potential. The contributions of 15 nations over the last decade have resulted in this unique resource with its access to the microgravity environment, stable viewpoints of Earth and space, as well as access to the orbital environment—namely radiation and the vacuum of space. But what does the cooperative environment that went into building the station mean for the long term science prospects that are now ramping up to their full potential?

The space station has become a scientific melting pot. Similar to the benefits that immigration brought to North America during the industrial revolution, the station is poised to provide benefits to the scientific community and any young pioneers willing to take up the challenge to use this outpost on the frontier of space. The station is also a U.S. National Laboratory, with research facilities that support human biomedical research, animal and plant physiology, materials science, fluid and combustion physics, remote Earth observations, and advanced engineering and technology demonstrations, side-by-side-by-side.

This multidisciplinary research facility presents a rare opportunity for researchers. The dedicated research facility is still much more common than the multidisciplinary facility, typically limiting researchers to just one field of scientific investigation.   Aboard station the experiments from these vastly different fields literally run right next to one another. The astronauts who make many of these investigations possible often have different scientific backgrounds from the principal investigators they are working with on the ground. This opens the potential for dialogue and insights as the studies progress.

The spirit of cooperation that was required in building the space station is still very much evident  today. Different investigations on board may cooperatively share equipment to accomplish their research objectives, minimizing the cost and mass to launch and maximizing the use of in-orbit resources.

One such example of resource sharing that is possible aboard station is in the sharing of camera equipment and software for the Binary Colloid Alloy Test (BCAT) and the Earth Knowledge Acquired by Middle School Students (EarthKAM). BCAT is a set of fluid physics experiments to examine the traits of super-critical fluids and phase separation of fluids. Meanwhile, EarthKAM is an educational outreach study focusing on remote Earth observation and using the capabilities of the EarthKAM camera to engage students, teachers and researchers in collaborative investigations. These two studies may seem worlds apart, but it is because the BCAT investigation is able to use the automated EarthKAM camera and software that BCAT was able to run many samples without requiring an undue amount of crew time.


EarthKAM equipment set up for a view of the Earth from the orbital perspective of the International Space Station. (NASA)


Astronaut Cady Coleman uses EarthKAM equipment to document an experiment run of the Binary Colloid Alloy Test (BCAT) study aboard the International Space Station. (NASA)

So why is multidisciplinary research a good thing to promote? For one thing, it often leads to innovation. The explanation for this is something we’ve all experienced from time to time. It’s much like when you get stuck on a problem. You can stare at it for hour upon hour and just not see the solution. Yet if the right friend happens along, they might see something you’ve been missing and the problem is solved in next to no time. Frustrating, sure, but sometimes a different perspective is all that is needed to reach a breakthrough.

Multidisciplinary science tries to capitalize on the benefits of having different scientific backgrounds engage and become part of the solution to a complex problem. Admittedly, a physicist and a biologist may look at a problem and see vastly different solutions, but when multiple disciplines and multiple participants work together to solve the same problem it opens the doorway to true innovation.

A great recent example is the interaction between the BCAT-6 principal investigator Matthew Lynch and Expedition 30 crew member Don Pettit. Lynch and Pettit worked together to achieve a more detailed image of the BCAT phase separation sample. Pettit suggested using a laser pointer source on orbit to attempt to reveal any diffraction—when light bends around an object—patterns that showed the structures and phase separation characteristics they were looking for. It worked! Innovation was born at the intersection of fluid physics, optical physics and chemical engineering.


Concept for how diffraction patterns can be detected from suspensions of colloidal particles. Irregular diffraction patterns result from irregular particle spacing, however, the presence of the pattern allows you to know when the colloidal particle groups are within the field of the camera. (Illustration by O.M. Yetfanov. Used with permission Journal of Biotechnology/A.P. Mancuso, O.M. Yetfanov, et. al.,)

Co-location is another obvious advantage of the station as a research platform. To date there have been several investigations directed at in-house resource production, such as Tomatosphere, which run in the LADA greenhouse and the Biomass Production System (BPS), to name a few. Additionally there have been multiple experiments designed to help better understand the burning of fuels in the Combustion Integrate Rack (CIR) and the Microgravity Science Glovebox (MSG), like the FLEX-2, SPICE and SLICE investigations. As a result of such studies, crew members may someday grow their own fruits and vegetables to eat or be able to fuel up the engines of the future.


NASA astronaut Mike Fossum, Expedition 28 flight engineer, inspects a new growth experiment on the BIO-5 Rasteniya-2 (Plants-2) payload with its LADA-01 greenhouse in the Zvezda service module of the International Space Station. (NASA)

When multidisciplinary science is brought into this picture, you can envision not only growing food aboard station, but processing those plants into biofuel and then testing its combustion capabilities. The context evolves into a larger study of in-orbit biofuel suitability. In fact, just because these resources are all available on station, researchers can propose new multidisciplinary studies to spur on scientific innovation.   


A burning heptane droplet during the FLEX investigation on the International Space Station. (NASA)

Another sign of the multidisciplinary research potential on station is the transformation of the American Society for Gravitational and Space Biology (ASGSB) into the American Society for Gravitational and Space Research (ASGSR). At the first ever ASGSR Annual meeting, held in December in New Orleans, researchers and students from a wide range of physical and biological sciences came together to discuss the possibilities and challenges of reduced gravity studies. The opportunity was an enlightening one for scientists in previously separated disciplines to come together and share information on their research programs, including many of the active areas of research done aboard station.

With collaborative efforts like these, the multidisciplinary research potential of the International Spaces Station is already being tapped. It will be exciting to see what discoveries will result from our orbiting, scientific melting pot in the years to come.

Kirt Costello completed a Ph.D. in Space Physics and Astronomy in 1998. While at Rice University, Costello worked on a magnetospheric forecast model used to predict the magnetic field response at the Earth’s surface based on upstream solar wind data. The model was used as a primary forecast model in this field at the Space Environment Center in Boulder, Colo., from 1997-2011. Since 2000, Costello has worked at NASA’s Johnson Space Center as a Thermal and Electrical Power Crew training instructor, as an International Space Station Training Lead, and as a group lead in the Mission Operations Directorate Operations Division. Kirt is now the Assistant International Space Station Program Scientist for National Research. In this position he works with the ISS Program Scientist to advise the ISS Program Manager on the objectives and priorities of science being prepared to fly to the space station.

 

The Tool to Fill the Gaps of our Senses: AMS

In today’s A lab Aloft blog entry, International Space Station Associate Program Scientist Tara Ruttley shares her point of view on the importance of asking the big questions via station research.

When I do public speaking events, people always ask me what’s my favorite investigation. For me it’s usually the Alpha Magnetic Spectrometer, or AMS investigation. This incredible instrument is a particle physics detector mounted to the outside of the International Space Station. The AMS was developed by Professor Samuel Ting, a Nobel Laureate in physics, along with an international collaboration of 16 countries organized by the U.S. Department of Energy.


Estimated distribution of dark matter making up 22 percent of the mass of the universe and dark energy making up 74 percent, with ‘normal’ matter making up only 0.4 percent of the mass of the universe. (NASA)

The goal of AMS is almost like sci-fi, involving the search for dark matter, dark energy, antimatter, and even something called strangelets. You hear about these things growing up and on TV and you wonder, is that real? If you go past the scientific jargon, the purpose of AMS is to answer a fundamental question in our nature. To ask, as we have from the beginning of time, how did the universe begin?

The answer to this question intrigues me, like everyone else, because it inevitably addresses “who are we and what are we doing here?” Everybody would love to know, so we seek the answers the best way that we humans can: pushing technology limits to find evidence in ways that our own human senses cannot.

The researchers behind AMS are trying to get solid data to support one of the more prevalent theories: the big bang. In a nutshell, this theory says that the universe came together, particles condensed, and boom! You got us. It’s a little more complicated than that, but the theory behind it is that for the big bang to even occur, you had to have equal parts matter and antimatter.

Matter is something we can see and feel, it’s all around us and makes up everything. It’s so very obvious! Antimatter is a little more tricky for us. It is the opposite of matter and we can theorize that it exists and even make small, fleeting samples in laboratories. And so we are using AMS to look for these things that we mere mortals aren’t capable of perceiving for ourselves.

AMS’s space shuttle-mounted predecessor actually found evidence of antimatter a few years ago, so we are only teased by this potential and are now prompted to capture the particles in greater, consistent amounts for study. Now we’re ready to collect lots of evidence for antimatter levels that will keep Nobel laureates, post-docs, and graduate students busy analyzing for years. Since its installation on station, which marked a one year anniversary on May 19, AMS has been collecting about a billion observations per month and even the smallest bits of data are going to lead to hundreds of publications. These will cite the importance of AMS findings with a relevance that likely only super smart astrophysicists will understand, and that the rest of us will see in headlines here and there as new evidence unfolds.


A close view of the Alpha Magnetic Spectrometer-2, or AMS, in the space shuttle Endeavour’s payload bay prior to being mounted to the International Space Station’s starboard truss. (NASA)

Using AMS, we record as much data as we can and analyze it here on Earth. This is where we try to tell an ultimate story with it. It’s what we do in science: chip away at a question until we can come to a conclusion that is always just beyond the next discovery. Yet, as exciting as the headlines will be, I actually tend to struggle with what’s next on these findings. I struggle because, since as we gain bits and pieces of knowledge, inevitably we learn not only what we didn’t know, but how much more there is to know.

Can you sense my impatience and excitement?

Observing antimatter is the first data goal that goes back to the big bang theory. The next data set AMS looks for is dark matter or dark energy, which is fun for me because it further proves that there’s more out there than meets the eye. We humans have senses for sight, sound, smell, taste, and touch, but we are limited to the capability of our receptors as we constantly take in our environment. We miss things that could be right there in front of us.

One of the limits of our eyesight, for instance, is that we can only see a certain spectrum of light. We don’t see the ghastly amounts of waves that pass all around us as our wireless devices talk to each other, or our radios blare during our morning jog. Our eyes see only 5 percent of the universe! We can sense that the other 95 percent of the universe exists, however, because we have found tantalizing evidence through research. We are using AMS as an extension of ourselves to fill in the gaps of our senses and help us understand the unknown. This includes the parts that we don’t even know we don’t know yet.


The starboard truss of the International Space Station is featured in this image, including the Alpha Magnetic Spectrometer-2, or AMS, at center left. (NASA)

AMS also is looking for evidence of a type of matter called strangelets. Yes, it does sound … well … strange. This would be a new form of matter that we have theorized existence of, but haven’t found in nature quite yet.

We’re taught in school that all matter is made of atoms, which we thought were the smallest form of matter. Now scientists are finding that atoms are made of even smaller quarks, and the prevailing theory regarding quarks is that there are six different types in the universe. We have classified all matter on Earth as being made up of only three types of quarks. So why does nature need the additional three? Some scientists theorize that there are other forms of matter out there that would be made up of a combination of these six quarks, and they’re calling them strangelets. It is a creative effort to try to answer what and where these strangelets are. Scientists have created such evidence as “strange” and “antistrange quarks” in heavy ion accelerators, which they theorize could lead to strangelet formation, but as of now, a strangelet is still a hypothetical particle. The prospects are endless.

Only the space station is capable of supporting the power and data transfer AMS requires to look for evidence of antimatter, dark matter, dark energy, and strangelets, and it will keep the scientific community busy for years. The human species develops tools like AMS to find the things we might otherwise miss, because we seek answers — lots of answers. It’s our nature.

AMS is an instrument that is taking it all in and ultimately it’s humans who will try to make sense of the information and apply it to what we know or think we know. We’ll learn what we didn’t know and try to tell our own local story. As we advance as a species, we build on that knowledge that may one day expand with the universe, beyond our little planet. It’s a good time to be a science geek.


Tara Ruttley, Ph.D.
(NASA Image)

Tara Ruttley, Ph.D., is Associate Program Scientist for the International Space Station for NASA at Johnson Space Center in Houston. Ruttley previously served as the lead flight hardware engineer for the ISS Health Maintenance System, and later for the ISS Human Research Facility. She has a Bachelor of Science degree in Biology and a Master of Science degree in Mechanical Engineering from Colorado State University, and a Doctor of Philosophy degree in Neuroscience from the University of Texas Medical Branch. Ruttley has authored publications ranging from hardware design to neurological science, and holds a U.S. utility patent.

Putting on a Thinking Cap for Brain Research on the Space Station

In today’s A Lab Aloft, guest blogger astronaut Bob Thirsk shares with readers his perspective as a test subject for International Space Station investigations.

I operated many different science payloads during my six-month International Space Station expedition in 2009. Some payloads only required me to power up and check out the hardware. Once activated, either automated software or the ground science team took control of payload operations and completed the rest of the experiment.

Neurospat, on the other hand, was a payload that fully engaged me in the science and data collection. A cognitive function experiment from Belgium and Hungary, it depended on astronauts to operate all aspects of the experiment from start to finish and even to serve as experiment test subjects. As a fundamental neuroscience research investigation, Neurospat may help researchers better understand the human brain and how it functions.

Frank De Winne, my European crewmate, and I were the very first subjects for Neurospat. When Frank served as a subject, I would help him set up the hardware. When I was a subject, Frank would help me in return. The biggest challenge of hardware setup was to place the cap on our crewmate’s head without laughing. It’s impossible to keep a straight face when your crewmate is wearing a scalp-hugging red or blue polka dot cap with an electrical pony-tail and wires dangling around the face. We looked like jesters! 

In reality, this odd-looking cap is a sophisticated electroencephalographic, or EEG, measurement device that incorporates 64 electrodes within the fabric to monitor our brain waves. A few other electrodes hanging from the cap are applied elsewhere on our skin to monitor eye movements, muscle activity and cardiac rhythm.

An important task of the assistant was to apply just the right amount of electro-conductive gel beneath each electrode using a syringe. The gel reduces the electrical impedance between the electrode and the subject’s scalp, improving the signal quality.


Bob Thirsk uses a syringe to inject a small amount of electro-conductive gel beneath each electrode of Frank De Winne’s EEG cap. Meanwhile, Frank initiates the Neurospat software for his upcoming experiment session. (NASA)

The pony-tail of the cap connects to the Multi-Electrode EEG Mapping Module—say that three times quickly!—which is a unit within a payload rack in ESA’s Columbus laboratory. This unit not only collected the data from the 64 electrodes, it also transmitted it to the ground. At the end of each Neurospat session, there was a lot of data that needed to be transmitted!

The fun began once the hardware was ready, the cables were connected and the data was flowing. For the next 70 minutes Frank and I repetitively performed four different experiment tasks while free-floating.

A computer screen, which we viewed through a tunnel adapter, presented specific tasks to us. Two of these tasks assessed our perception of visual orientation. Using buttons on a keypad, we evaluated the orientations of lines and estimated the locations of dots on the face of an imaginary clock face. This portion of the experiment was tedious. Frank and I joked to ourselves that while Neurospat claims to be a cognitive function experiment, this portion of the experiment was secretly a sleep induction investigation!

The other two Neurospat tasks were visuomotor “docking” tasks that kept us attentive and wide awake. The objectives were to alternately pilot a simulated Soyuz-like vehicle to a docking port on the space station, or to manually dock a Progress-like vehicle as if we were a cosmonaut working from a control station inside the station. This was similar to a video game requiring the use of a joystick. As we worked to complete each docking task quickly and accurately, the EEG cap monitored the functions of our cerebral cortex. I loved this portion of the experiment, since the tasks appealed to my competitive instincts.


After the Neurospat equipment has been set up, the free-floating test subject performs 70 minutes of cognitive function tasks. (NASA)

Researchers are already analyzing the data from Frank, myself, and all of the other astronauts who have participated in Neurospat to date. They compare our performance in space to our performance on the ground, both before and after flight. The scientists are particularly interested in our brain wave patterns, since these provide insight into our neural and cognitive processes while we performed the tasks.

Scientists hypothesize that long-duration spaceflight affects an astronaut’s sensorimotor system and cognitive abilities. Specifically, they think astronauts may have difficulty determining which way is up, and that our cognitive processes in space may be degraded by stress, fatigue and disrupted sleep.

Neurospat data collection is scheduled to continue on the station through September 2012. The research team expects to have enough astronaut subjects by the end of this year to complete their analysis and publish their results. I enjoyed Neurospat, as it was an experiment that fully engaged me in the science and data collection, putting my training and skills to the test. For an astronaut who is interested in payload operations, it doesn’t get any better than that.


Dr. Robert (Bob) Thirsk is an astronaut with the Canadian Space Agency. He holds degrees in mechanical engineering, an MBA, and is also a medical doctor. Dr. Thirsk has been involved in various Canadian Space Agency and NASA projects and is a veteran of two space flights: STS-78 in 1996 and Expedition 20-21 in 2009.

Ringing Out 2012 by Chiming in on International Space Station Achievements

In today’s A Lab Aloft International Space Station Program Scientist Julie Robinson looks back at the year in review for research aboard the orbiting laboratory.

As the year comes to a close, I like to take a moment to look back at all the amazing accomplishments from the previous twelve months for the International Space Station. There are lessons to be learned and goals to be evaluated as part of planning for the new year. But this is also a time to enjoy achievements and strides made via this orbiting laboratory in research, technology and education.

Keeping a Helpful Eye on Earth

The vantage point of station offers not only an impressive view of our planet, but the chance to capture and study important aspects of the Earth’s atmosphere, waters, topography and more. The 2012 arrival of the ISS SERVIR Environmental Research and Visualization System, known as ISERV, will enhance the viewing capabilities from orbit used to support disaster assessment, humanitarian assistance and environmental management.

This year an externally-mounted station instrument contributed to the Environmental Protection Agency’s goal of monitoring and improving coastal health. The same Hyperspectral Imager for the Coastal Ocean, or HICO, also assists the National Oceanic and Atmospheric Administration, or NOAA, with scans to determine depth below murky waters, bottom type, water clarity and other water optical properties.

Assisting with disaster response became the secondary mission for the International Space Station Agricultural Camera, or ISSAC. This imager was originally intended for agriculture vegetation surveys to assist with crop and grazing rotation. When that primary science objective ended, the camera became part of the space station’s response efforts for global disasters as part of the International Disaster Charter.


Map of chlorophyll-a for Pensacola Bay derived from HICO data. Higher values (yellow and red) indicate high chlorophyll concentrations in the water that suggest algal blooms are present. Algal blooms can reduce oxygen levels in the water, leading to fish and other animal kills. Some algal blooms also contain organisms that produce toxins harmful to other life, including humans. (EPA)

Inspiring Future Generations

This year NASA’s continued support in educational areas of science, technology, engineering and math (STEM) led to some exciting student-based activities and resources. With the Student Spaceflight Experiment Program, or SSEP, for instance, 15 investigations were selected from close to 800 proposals of student inspiration and design. The results from these studies will be shared at the national conference held each year in Washington DC.

The YouTube Space Lab competition provided another opportunity that caught the attention and imagination of students around the world. Two investigations were selected as winners from more than 2,000 video submissions and many tuned in to watch as the experiments were conducted by astronauts live on orbit.

You can read about all of the education activities available to students to participate in space station science in our recently published “Inspiring the Next Generation: International Space Station Education Opportunities and Accomplishments, 2000-2012.” This retrospective book details station activities involving more than 42 million students and 2.8 million teachers across 48 countries from 2000 to 2012.


Joseph Avenoso (left), Gage Cane-Wissing (right), and Adam Elwood (not pictured), presented their findings on bone loss in microgravity as part of the 2012 SSEP National Conference. (NCESSE/Smithsonian)

Technology Testbed

The space station plays an important role as a microgravity testbed for emerging technologies. The JEM-Small Satellite Orbital Deployer, or J-SSOD, for instance, operated for the first time in 2012, launching multiple small satellites into orbit. This new capability provides a reliable, safe and economically viable deployment method for releasing small satellites, in addition to enabling the return samples to the ground for analysis.

Another exciting technology tested on station is the Robotic Refueling Mission, or RRM, which may help support future space exploration using advanced robotics to service vehicles and satellites in orbit. This capability does not currently exist, but is essential to long-duration exploration missions of tomorrow.


JAXA astronaut Aki Hoshide preparing the JEM Small Satellite Orbital Deployer aboard the International Space Station. (NASA)

Exciting Discoveries for Human Health and Science Disciplines

Findings from station investigations are impacting human health both here on Earth and in orbit. For instance, recently published results related to bone health showed that a combination of nutrition, Vitamin D supplements, and high-intensity resistive exercise help the crew to preserve bone mass density without the need for pharmaceuticals. These findings also apply to the development of treatments for osteoporosis patients here on Earth, an estimated 44 million in the United States alone.

Crew health was highlighted in vision studies in 2012, as well, with the publication of two results papers focused on the impact of microgravity on astronaut vision changes. Research found that significant vision loss in 20 percent of crew members may derive from a combination of the spaceflight environment and changes in metabolism, with an enzyme related to cardiovascular health potentially playing a role.

A discovery of “Cool Flames” caused excitement in the physical sciences community this year. These low-temperature flames ignite via chemical reactions from fuel vapor and air, burning invisible to the eye. This knowledge can help with improving fire safety in orbit, but also has implications for cleaner and more fuel efficient combustion in engines here on Earth.


A burning heptane droplet during the FLEX investigation on the International Space Station. (Credit: NASA)

Ringing in the New Year

Looking forward to 2013, there are still so many exciting things to learn in the various disciplines studied aboard station. Whether in biology and biotechnology, Earth and space science, human research, the physical sciences or even technology developments, there remains a huge potential for discovery. The advent of updated and new facilities planned for the station will help enable investigators in their research in these areas.

Along with the research taking place aboard station, we continue to see Earth benefits that derive either directly or as a spinoff of station science. I look forward to continuing to share these findings and stories with you in the coming year and through the lifetime of this amazing microgravity laboratory.

Julie A. Robinson, Ph.D.
International Space Station Program Scientist

 

Remembering Dr. Bob Phillips

In today’s A Lab Aloft we remember Dr. Bob Phillips, who served as the chief scientist for Space Station Freedom, helping to pave the path for future research in orbit.

While I did not have the pleasure of working directly with Dr. Bob Phillips, he helped blaze a trail for research in space that played an important part in what eventually became the International Space Station (ISS) Program.

A doctor of veterinary medicine with a Ph.D. in physiology and nutrition, Bob started his career with NASA in 1984. Part of Spacelab Life Sciences (SLS) 1, which launched aboard space shuttle Columbia’s STS-40 mission in 1991, Bob had planned to serve as an astronaut payload specialist, but was grounded due to a minor medical condition. Instead, he played a key role as the principal radio contact between the crew and ground while they conducted the first mission dedicated to microgravity biomedical research.

Bob followed the SLS-1 mission with a three-year stint as chief scientist of Space Station Freedom, which evolved into today’s International Space Station. As the current space station program scientist, I can’t help but look back at Bob’s accomplishments and be inspired in my own goals and endeavors for research in orbit.

Mark Uhran, former assistant associate administrator for the International Space Station, recalls the contributions made by Bob during his tenure. “During the space station design phase, Bob Phillips was a pivotal voice in mediating between science and engineering to develop research requirements that were practical and achievable. He served as both chief scientist and as a member of the Space Station Utilization Advisory Subcommittee, where his pragmatic approach was invaluable in resolving a final design for what later became the ISS.”


Robert W. Phillips (Credit: Colorado State)

I recently spoke about Bob’s contributions to NASA with my colleague Jennifer Rhatigan, Ph.D., who was a leader in space station science during the station’s assembly and established the International Space Station Program Science Office. Jennifer, who served with Bob on a number of committees, remembered him not only as a scientist, but also as a gentleman who was a pleasure to work with.

“Bob brought a focus on science in the early days of the space station design (during the Freedom program),” Jennifer shared. “He recognized that science needs had to be part of the design and maintained that focus through the many early de-scopes and design changes. The space station science community of today is lucky there were people like Bob looking out for their needs 25 years ago.”

Bob continued his career with NASA and into retirement with a focus on outreach and education. According to his NASA Quest profile, Bob espoused a belief in lifelong learning and continued scientific endeavors.

“I don’t feel that I have any goals yet to accomplish, except to continue to accomplish and pursue new and interesting questions and challenges. I have retired several times and look forward to continuing to be a productive scientist educator. I am having too much fun to really quit.”

Bob passed away on Feb. 26, leaving behind a rich legacy including a book he wrote to communicate with the general public the importance of biomedical microgravity research, titledGrappling with Gravity: How Will Life Adapt to Living in Space?”

When I think about where we are now with research aboard the space station after more than a year of full utilization, I am still in awe of the accomplishments that are shared by those who contributed past, present and future to the station’s success. The flexible and adaptable laboratory we have today was built on the foundation of hard work and dedication from people like Bob Phillips and the way he helped to put science into an engineering marvel.


Julie A. Robinson, Ph.D.
International Space Station Program Scientist

SAGE Wisdom for Atmospheric Research

In today’s A Lab Aloft, guest blogger Kristyn Damadeo shares the history of the SAGE investigation, scheduled for future use on the International Space Station. This technology can help researchers to better understand Earth’s atmosphere makeup, especially the health of our ozone layer.

The International Space Station houses some unique experiments and soon it will be home to an exciting new Earth science mission: SAGE III, the Stratospheric Aerosol and Gas Experiment III.

SAGE III mounts externally to the space station and is a mission to study Earth’s atmosphere sponsored by the NASA Science Mission Directorate and led by NASA Langley Research Center. It will be the first Earth-observing instrument of its kind aboard station, taking accurate measurements of the amount of ozone, aerosols—tiny particles—water vapor and other key components of Earth’s atmosphere.

The SAGE Legacy

SAGE III is the first of its kind to operate on station, but the SAGE family of instruments has been taking atmospheric measurements for more than 30 years. SAGE III is the fourth generation in its family operated by NASA.

The artwork above belongs to the SAGE III instrument, which is part of a family of SAGE technology developed to help research Earth’s atmosphere. (NASA Image)

The first SAGE instrument was flown on a satellite in 1979. SAGE I was a sun photometer that used solar occultation—a measurement technique using the sun as a backlight—to gather information on aerosols and important stratospheric gases in the atmosphere. SAGE I collected valuable data for nearly three years, until the power system on the satellite failed.

With SAGE I came the start of a global database for stratospheric aerosols, ozone, and nitrogen dioxide that is still used in the study of global climate. While SAGE I was active, it provided crucial input into the understanding of global, seasonal and inter-annual variability in climate and, in particular, trends in stratospheric ozone.

SAGE I was followed by SAGE II in 1984. SAGE II data helped to confirm human-driven changes to ozone and contributed to the 1987 Montreal Protocol, which banned the use of chemicals that harm the ozone layer. SAGE II lasted 21 years on orbit, allowing us not only to determine the initial extent of ozone changes, but also to measure the effectiveness of the Montreal Protocol. SAGE II saw ozone stop decreasing and begin to recover during its time on orbit.


Engineers at NASA Langley work in a clean room with the SAGE III instrument. (NASA Image)

Then in the late 1990s, SAGE III was developed by Ball Aerospace and Technology Corp. The first of the instruments was launched in 2001 on a Russian satellite, METEOR-3M. The second instrument was stored for a future flight of opportunity. The third was removed from storage and prepared for flight on the space station. The mission will enable researchers to fill an anticipated gap in ozone and aerosol data in the second half of this decade.

Ozone

SAGE III will study Earth’s protective ozone layer from aboard station. Ozone acts as Earth’s sunscreen. When ozone starts to break down, it impacts all of Earth’s inhabitants. Humans, plants and other animals are exposed to more harmful rays from the sun. This can cause long-term problems, such as cataracts and cancer in humans or reduced crop yield in plants.

When SAGE III begins making measurements from the space station in late 2014, some models predict that stratospheric ozone should have recovered by 50 percent. The precise pattern of ozone recovery measured by SAGE III will help improve the models and refine our understanding of the atmosphere.


Particles in the upper Earth’s atmosphere cause the blue layer shown in this image of a sunrise taken from aboard the space station. SAGE III will measure these atmospheric gases from a similar perspective. (NASA Image)

Measurement Technique

SAGE III takes its measurements using solar and lunar occultation. Occultation is a technique for pointing and locking onto the sun or the moon and scanning the limb—thin profile—of the atmosphere as the sun or moon rises or sets. SAGE III will operate mostly autonomously and the data will be transmitted to the ground through the space station’s communications systems.

The space station provides the perfect orbit from which to take measurements of the composition of the middle and lower atmosphere. Our location aboard station also gives us a great view for our solar/lunar occultation technique.

Back in Action

SAGE III is scheduled to launch to the space station aboard a SpaceX Falcon 9/Dragon in mid-2014.

The SAGE III suite consists of a sensor assembly that has pointing and imaging subsystems and an ultraviolet/visible spectrometer; an European Space Agency- provided hexapod pointing system and a nadir viewing platform. The Canadian Space Agency-provided robotic arm will robotically move SAGE III from the Dragon trunk and install it on the Earth-facing side of the EXPRESS Logistics Carrier-4, or ELC 4, storage platform. 

The graphic above depicts the SAGE III instrument, which will collect data to help researchers better understand Earth’s atmosphere. (NASA Image)

The research results of the space station-mounted SAGE III will provide insights that will help humans better understand and protect Earth’s atmosphere. Only by understanding these changes will we be able to mediate future impacts on our environment. Much more data and research is needed to better understand and quantify our impact on our world’s climate system.

The SAGE program has a long heritage and is one of NASA’s longest running Earth-observing programs. Continuous long-term data collection is necessary to understand climate. Once it is on the space station, SAGE III will help to extend a long record of atmospheric measurements for the continued health of our Earth. The observations of SAGE III from station are crucial for providing a better understanding of how natural processes and human activities may influence our climate.

SAGE has been pivotal in monitoring ozone and making accurate measurements of the amount of ozone loss in Earth’s atmosphere. Today, the SAGE technique is still the best for the job. Although new technologies have come along to measure ozone, none are as thorough as solar occultation. Through this dataset, SAGE on the station will enhance our understanding of ozone recovery and climate change processes in the upper atmosphere. We also extend the scientific foundation for further sound decisions on environmental policy, both nationally and internationally.


Kristyn Damadeo is the Education and Public Outreach Lead for SAGE III on the International Space Station at NASA’s Langley Research Center in Hampton, Va. She has previously worked as a science writer and a newspaper reporter, specializing in environmental reporting. Damadeo has a degree in Communication Arts from Ramapo College of New Jersey.